User:Jadrian Miles/Diffusion simulation

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  • Axon gauges in range 0.25 -- 10 μm (wzhou cite 1)
  • Hindered diffusion differs from free diffusion by a "tortuosity" value (Nicholson "Diffusion and related transport mechanisms" '01)
  • Volume fraction is ~80% intra? (Nilsson MRI '08)
  • Extracellular free D ~= 1.08 μm2/ms (ibid)
  • τintra ~= 306 ms (but authors claim it's a bad fit) (ibid) (exchange times; see page 178 and ref 35)


Human histology would be useful: hand-compute volume fraction of intracellular fluid, extracellular fluid, and myelin, as well as axon gauges.