User:Jadrian Miles/Diffusion simulation: Difference between revisions
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New page: * Axon gauges in range 0.25 -- 10 μm (wzhou cite 1) * Hindered diffusion differs from free diffusion by a "tortuosity" value (Nicholson "Diffusion and related transport mechanisms" '01)... |
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* Axon gauges in range 0.25 -- 10 μm (wzhou cite 1) | * Axon gauges in range 0.25 -- 10 μm (wzhou cite 1). "Extra-thick" axons (~20μm) are rare; about 3% occurrence at most, and only in certain structures. | ||
* Hindered diffusion differs from free diffusion by a "tortuosity" value (Nicholson "Diffusion and related transport mechanisms" '01) | * Hindered diffusion differs from free diffusion by a "tortuosity" value (Nicholson "Diffusion and related transport mechanisms" '01) | ||
* Volume fraction is ~80% intra? (Nilsson MRI '08) | * Volume fraction is ~80% intra? (Nilsson MRI '08) | ||
Revision as of 00:47, 24 March 2009
- Axon gauges in range 0.25 -- 10 μm (wzhou cite 1). "Extra-thick" axons (~20μm) are rare; about 3% occurrence at most, and only in certain structures.
- Hindered diffusion differs from free diffusion by a "tortuosity" value (Nicholson "Diffusion and related transport mechanisms" '01)
- Volume fraction is ~80% intra? (Nilsson MRI '08)
- Extracellular free D ~= 1.08 μm2/ms (ibid)
- τintra ~= 306 ms (but authors claim it's a bad fit) (ibid) (exchange times; see page 178 and ref 35)
Human histology would be useful: hand-compute volume fraction of intracellular fluid, extracellular fluid, and myelin, as well as axon gauges.